刘艺云，女，博士，副教授，硕士生导师。

主要从事细菌耐药性产生和传播机制研究。担任Int J Antimicrob Agents、Commun Biol和Antimicrob Agents Chemother等杂志审稿人。曾获得北京市自然科学一等奖，入选中国高被引学者。

2016.09–2020.12：          博士

2018.05–2019.06：澳大利亚莫纳什大学    博士联合培养

2015.12–2016.03：美国匹茨堡大学        访问学者

2013.09–2016.06：          硕士

2009.09–2013.06：福建农林大学          学士

2021年1月至今， 兽医学院，药理教研室，副教授

耐药性产生和传播机制

药物敏感性检测和耐药性监测

国家自然科学基金青年科学基金，2022-2024，主持

广东省普通高校省级重大科研项目青年创新人才项，2021-2023，主持

广州市基础研究计划基础与应用基础研究，2022-2024，主持

 “突出人才”人才引进科研启动项目，主持

1.Yaoyao Lu, Jian-Hua Liu*, Chao Yue, Phillip J Bergen, Renjie Wu, Jian Li*, Yi-Yun Liu*. Overexpression of mcr-1 disrupts cell envelope synthesis and causes the dysregulation of carbon metabolism, redox balance and nucleic acids[J]. Int J Antimicrob Agents. 2022 Jul 21;106643. 

2.Liu YY †, Zhou Q †, He W, et al.. mcr-1 and plasmid prevalence in Escherichia coli from livestock[J]. Lancet Infect Dis. 2020, 20 (10):1126. 

3.Liu YY†, Wang Y†, Walsh T R, et al.. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study[J]. Lancet Infect Dis. 2016,16 (2):161-168. 

4.Liu YY, Chen Shen, Burrus Vincent, et al.. Editorial: Globally or Regionally Spread of Epidemic Plasmids Carrying Clinically Important Resistance Genes: Epidemiology, Molecular Mechanism, and Drivers[J]. Front Microbiol. 2021, 24, 12:822802. 

5.Liu YY†, Gao Xun†, He Xiaotong et al.. Emergence of the tigecycline resistance gene cluster tmexCD1-toprJ1 in an IncC plasmid and Citrobacter portucalensis[J]. J Antimicrob Chemothe. 2022, Apr 22;dkac136. 

6.Liu YY†, Chandler CE†, Leung, et al.. Structural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens[J]. Antimicrob Agents Chemother. 2017, 24;61(6).

7.Liu YY, Zhu Y, Wickremasinghe H, et al.. Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli[J]. Front Microbiol. 2020, 9, 11:588658. 

8.Liu YY, Liu JH. Monitoring Colistin Resistance in Food Animals, An Urgent Threat[J]. Expert Rev Anti Infect Ther. 2018, 16(6):443-446. 

9.Zhu XQ†, Liu YY†, Renjie Wu et al.. Impact of mcr-1 on the Development of High Level Colistin Resistance in Klebsiella pneumoniae and Escherichia coli[J]. Front Microbiol. 2021, 26;12:666782. 

10.Yi L, Liu YY, Wu R, et al.. Research progress on the plasmid-mediated colistin resistance gene mcr-1[J]. Yi Chuan. 2017, 20;39(2):110-126.

11.Yi L, Wang J, Gao Y, Liu YY, et al.. mcr-1-Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China [J]. Emerg Infect Dis. 2017, 23(2):291-295. 

12.Yang X, Liu W, Liu YY, et al.. F33: A-: B-, IncHI2/ST3, and IncI1/ST71 plasmids drive the dissemination of fosA3 and blaCTX-M-55/-14/-65 in Escherichia coli from chickens in China[J]. Front Microbiol. 2014, 16; 5:688. 

13.Wu R, Yi LX, Yu LF, Wang J, Liu YY, et al.. Fitness Advantage of mcr-1-Bearing IncI2 and IncX4 Plasmids in Vitro[J]. Front Microbiol. 2018, 27; 9:331.   

14.Lv L, Huang X, Wang J, Huang Y, Gao X, Liu YY, et al.. Multiple Plasmid Vectors Mediate the Spread of fosA3 in Extended-Spectrum-β-Lactamase-Producing Enterobacterales Isolates from Retail Vegetables in China[J]. mSphere.2020, 15;5(4). 

15.Huang X, Yu L, Chen X, Zhi C, Yao X, Liu YY, et al.. High Prevalence of Colistin Resistance and mcr-1 Gene in Escherichia coli Isolated from Food Animals in China[J]. Front Microbiol. 2017, 4;8:562.

16.刘艺云，邓利敏，岳慧颖，岳超，刘健华. 质粒接合转移及其抑制剂的研究进展[J]. 生物技术通, 2022, 38(9).

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