曾振灵，男，1963年4月出生于广东省兴宁市，农学博士，二级教授 。

    广东省高等学校“千百十工程”国家级培养对象；曾任国务院兽医专业学位教育指导委员会委员、教育部高等学校动物医学专业教学指导委员会委员、中国畜牧兽医学会兽医药理毒理学分会理事长。目前担任国家兽药残留基准实验室（SCAU）主任、国家兽药安全评价（环境评估）实验室（SCAU）主任、广东省兽药研制与安全评价重点实验室主任、广东省高校兽药创新工程技术研究中心主任。兼任中国畜牧兽医学会兽医药理毒理学分会副理事长、中国畜牧兽医学会动物毒物学分会副理事长、中国毒理学会兽医毒理学分会副主任委员、农业部第一届农产品质量安全专家组成员、第一届食品安全国家标准审评委员会委员、中国兽药典第四、五届委员会和执行委员会委员、农业部第二、三届兽药残留专家委员会委员等。1996年在 获得兽医药理学与毒理学专业、农学博士学位。1997年破格晋升为教授。

    20多年来，长期从事兽医药理学与毒理学研究，在兽医药代动力学、新兽药研发与安全评价、动物源性食品安全与兽药残留、细菌耐药机制等方面开展了系列研究工作，相关研究成果已发表SCI收录论文80余篇，影响因子累计超过230，被引用800多次。出版专著、教材、科普书10部。获授权发明专利20多项，国家级新兽药证书3个。

    曾获“广东省优秀博士”、 “广东省高等学校千百十工程国家级人选”、“南粤优秀教师”、“广东省优秀博士论文指导教师”、“全国兽医硕士专业学位优秀论文指导教师”等荣誉。获国家科技进步二等奖1项；省部级科技进步一等奖3项、二等奖1项、三等奖3项。获国家教学成果二等奖1项，省级教学成果一等奖1项、二等奖1项；全国高等农业院校优秀教材；国家精品课程1门，国家精品资源共享课程1门，广东省精品课程1门； 教学名师。

《 学报》编委员会委员(2015—现在)

《中国兽医学报》编委员会委员(2006—现在)

《动物医学进展》编委员会委员(2006—现在)

《中国兽药杂志》编委员会委员(2009—现在)

《中国家禽》编委员会委员(2008—现在)

《广东畜牧兽医科技》编委员会委员（2008—现在） 　

1991年9月－1996 年6月 动物医学系兽医药理学与毒理学专业博士研究生，获农学博士学位。

1984年9月－1987年9月 动物医学系兽医药理学与毒理学专业硕士研究生，获农学硕士学位。1979年7月－1984年7月 华南农学院畜牧兽医系兽医专业本科生，获农学学士学位。

2002年4月～2003年4月 美国University of Illinois at Champaign-Urbana兽医学院做高级访问学者。

1987.07起在 兽医学院一直从事兽医药理学与毒理学的教学科研工作。晋升教员（1987.07～1990.05），讲师（1990.06～1993.09），破格晋升副教授（1993.10～1997.11），硕士生导师（1994），破格晋升教授（1997.12～），博士生导师（1998），二级教授（2011.01～

1998.05～2000.01任 动物医学系副主任；2001.05～2007.01任兽医学院院长；2000.01～2007.01任农业部畜禽产品质量监督检验测试中心（广州）副主任；2007.01～2015.06任农业部畜禽产品质量监督检验测试中心（广州）常务副主任。

2007.01～现在 国家兽药残留基准实验室（SCAU）主任、国家兽药安全评价（环境评估）实验室（SCAU）主任、广东省兽药研制与安全评价重点实验室主任、广东省高校兽药创新工程技术研究中心主任、兽医药理研究室主任。

·新兽药的药代动力学、药效学

·兽药研制与安全性评价

·兽药残留与动物源性食品安全

·细菌对抗菌药的耐药机制

·国家重点基础研究发展计划（973项目）：畜禽病原菌重要耐药基因的传播机制与流行规律”（2013CB20703），2013～2017，主持

·国家自然科学基金面上项目：马波沙星与头孢喹肟半体内和体内药动药效学同步模型研究（31372480），2014～2017，主持

·农业部专项：兽药安全监管与风险评估（农财发2013、2014、2015）2014～2016

·教育部“创新团队发展计划”：兽用抗菌药安全性评价研究，2014～2016，参加

·广东省自然科学基金研究团队项目：畜禽重要病原菌耐药机制及防控技术研究，2014～2017, 参加

[1] W. Xiong, M. Wang, J. Dai, Y. Sun, Z. Zeng*, Application of manure containing tetracyclines slowed down the dissipation of tet resistance genes and caused changes in the composition of soil bacteria, Ecotoxicology and environmental safety, 147 (2018) 455-460.

[2] D. Zeng, Z. Lin, B. Fang, M. Li, R. Gehring, J.E. Riviere, Z. Zeng*, Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling, Journal of agricultural and food chemistry, 65 (2017) 5768-5777.

[3] M. Wang, Y. Sun, P. Liu, J. Sun, Q. Zhou, W. Xiong, Z. Zeng*, Fate of antimicrobial resistance genes in response to application of poultry and swine manure in simulated manure-soil microcosms and manure-pond microcosms, Environmental Science and Pollution Research, 24 (2017) 20949-20958.

[4] J. Guo, E.W. Chan, S. Chen, Z. Zeng*, Development of a Novel Quantum Dots and Graphene Oxide Based FRET Assay for Rapid Detection of invA Gene of Salmonella, Frontiers in microbiology, 8 (2017) 8.

[20] D. He, L. Liu, B. Guo, S. Wu, X. Chen, J. Wang, Z. Zeng*, J.H. Liu, Chromosomal location of the fosA3 and blaCTX-M genes in Proteus mirabilis and clonal spread of Escherichia coli ST117 carrying fosA3-positive IncHI2/ST3 or F2:A-:B- plasmids in a chicken farm, International journal of antimicrobial agents, 49 (2017) 443-448.

[5] X. Huang, L. Yu, X. Chen, C. Zhi, X. Yao, Y. Liu, S. Wu, Z. Guo, L. Yi, Z. Zeng*, J.H. Liu, High Prevalence of Colistin Resistance and mcr-1 Gene in Escherichia coli Isolated from Food Animals in China, Frontiers in microbiology, 8 (2017) 562.

[6] J. Wang, X. Yao, J. Luo, L. Lv, Z. Zeng*, J.H. Liu, Emergence of Escherichia coli co-producing NDM-1 and KPC-2 carbapenemases from a retail vegetable, China, The Journal of antimicrobial chemotherapy, (2017).

[7] L. Yi, J. Wang, Y. Gao, Y. Liu, Y. Doi, R. Wu, Z. Zeng, Z*. Liang, J.H. Liu, mcr-1-Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China, Emerging infectious diseases, 23 (2017) 291-295.

[8] Y. Li, Y. Zhang, H. Ding, X. Mei, W. Liu, J. Zeng, Z. Zeng*, In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin, BMC veterinary research, 12 (2016) 250.

[9] W. Xiong, Y. Sun, X. Ding, M. Wang, Z. Zeng*, Selective pressure of antibiotics on ARGs and bacterial communities in manure-polluted freshwater-sediment microcosms, Frontiers in microbiology, 6 (2015) 194.

[10] W. Xiong, Y. Sun, X. Ding, Y. Zhang, X. Zhong, W. Liang, Z. Zeng*, Responses of plasmid-mediated quinolone resistance genes and bacterial taxa to (fluoro)quinolones-containing manure in arable soil, Chemosphere, 119 (2015) 473-478.

[11] W. Xiong, Y. Sun, T. Zhang, X. Ding, Y. Li, M. Wang, Z. Zeng*, Antibiotics, Antibiotic Resistance Genes, and Bacterial Community Composition in Fresh Water Aquaculture Environment in China, Microbial ecology, (2015).

[12] C. Cao, Y. Qu, M. Sun, Z. Qiu, X. Huang, B. Huai, Y. Lu, Z. Zeng*, In vivo antimicrobial activity of marbofloxacin against Pasteurella multocida in a tissue cage model in calves, Frontiers in microbiology, 6 (2015) 759.

[13] D. He, J. Chiou, Z. Zeng, L. Liu, X. Chen, L. Zeng, E.W. Chan, J.H. Liu, S. Chen, Residues Distal to the Active Site Contribute to Enhanced Catalytic Activity of Variant and Hybrid beta-Lactamases Derived from CTX-M-14 and CTX-M-15, Antimicrobial agents and chemotherapy, 59 (2015) 5976-5983.

[14] F. Yang, J. Kang, F. Yang, Z. Zhao, T. Kong, Z. Zeng*, Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats, Journal of Veterinary Science, 16 (2015) 157.

[15] L. Liu, D. He, L. Lv, W. Liu, X. Chen, Z. Zeng, S.R. Partridge, J.H. Liu, blaCTX-M-1/9/1 Hybrid Genes May Have Been Generated from blaCTX-M-15 on an IncI2 Plasmid, Antimicrobial agents and chemotherapy, 59 (2015) 4464-4470.

[16] Y. Qu, Z. Qiu, C. Cao, Y. Lu, M. Sun, C. Liang, Z. Zeng*, Pharmacokinetics/pharmacodynamics of marbofloxacin in a Pasteurella multocida serious murine lung infection model, BMC veterinary research, 11 (2015) 294.

[17] Q. Shan, C. Liang, J. Wang, J. Li, Z. Zeng*, In vivo activity of cefquinome against Escherichia coli in the thighs of neutropenic mice, Antimicrobial agents and chemotherapy, 58 (2014) 5943-5946.

[18] J. Wang, Q. Shan, H. Ding, C. Liang, Z. Zeng*, Pharmacodynamics of cefquinome in a neutropenic mouse thigh model of Staphylococcus aureus infection, Antimicrobial agents and chemotherapy, 58 (2014) 3008-3012.

[19]Yang, F., Li, Z.L., Shan, Q., Zeng., Z.L*. Pharmacokinetics of doxycycline in tilapia (Oreochromis aureus x Oreochromis niloticus) after intravenous and oral administration, Journal of Veterinary Pharmacology and Therapeutics, (2014), 37(4):388-393.

[20] G.H. LI, Q. SHAN, J. WANG, Y.F. LI, Y. GAO, Z.L. ZENG*. Metabolism of Mequindox in Isolated Rat Liver Cells, Journal of Integrative Agriculture, (2014), 13(1), 158-166.

[21] J. Shu, L. He, H. Ding, L. Wang, H. Guo, Y. Gao, E. E. Dzakah, Z. Zeng*. Synthesis of furaltadone metabolite, 3-amino-5-morpholinomethyl-2 oxazolidone (AMOZ) and novel haptens for the development of a sensitive enzyme-linked immunosorbent assay (ELISA), Analytical Methods. (2014), 6(1): 2306-2313.

[22] X.M. Liang, G.F. Guo, X.H. Huang, W.L. Duan, Z.L. Zeng*. Isotetrandrine protects against lipopolysaccharide-induced acute lung injury by suppression of mitogen-activated protein kinase and nuclear factor-kappa B, Journal of Surgical Research, (2014), 187(2), 596-604

[23] Z.L. Zeng, H.-. Wei, J. Wang, D.C. Lin, X.Q. Liu, J.H. Liu. High prevalence of cfrproducing Staphylococcus species in retail meat in Guangzhou, China, BMC microbiology, (2014), 14: 151-156.

[24] Liqi Wang, Zhenling Zeng, Xianhui Huang,Yijuan Sua and Limin He. Matrix effects caused by phospholipids in multiresidue analysis for beta-agonists with liquid chromatography- electrospray tandem mass spectrometry, RSC Advances, (2014), 4: 25719-25728.

[25] Shan, Q., Liang, C., Wang, J., Li, J., and Zeng, Z*. In Vivo Activity of Cefquinome against Escherichia coli in the Thighs of Neutropenic Mice. Antimicrobial Agents and Chemotherapy, (2014), 58(10): 5943-5946.

[26] Wang, J., Shan, Q., Ding, H., Liang, C., and Zeng, Z*. Pharmacodynamics of Cefquinome in a Neutropenic Mouse Thigh Model of Staphylococcus aureus Infection. Antimicrobial Agents and Chemotherapy, (2014), 58(6): 3008-3012.

[27] Shan, Q., Yang, F., Wang, J., Ding, H., He, L., and Zeng, Z*.  Pharmacokinetic/pharmacodynamic relationship of cefquinome against Pasteurella multocida in a tissue-cage model in yellow cattle. Journal of Veterinary Pharmacology and Therapeutics, (2014), 37(2):178-185.

[28] Shan, Q., Wang, J., Yang, F., Ding, H., Liang, C., Lv, Z., and Zeng, Z*. Pharmacokinetic/pharmacodynamic relationship of marbofloxacin against Pasteurella multocida in a tissue-cage model in yellow cattle. Journal of Veterinary Pharmacology and Therapeutics, (2014), 37(3): 222-230.

[29] Yang F, Sun N，Sun Y X， Shan Q， Zhao H Y， Zeng  D P， Zeng ZL*. A physiologically based pharmacokinetics model for florfenicol in crucian carp and oral-to-intramuscular extrapolation. Journal of Veterinary Pharmacology and Therapeutics, (2013)，36（2）:192-200

[30] Yang, F., G.H. Li, X.B. Meng, L.Q. Wang, X.H. Huang, Q. Shan, D.P. Zeng, H.Z. Ding, and Z.L. Zeng*. Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens. Journal of Veterinary Pharmacology and Therapeutics, (2013), 36(1): 85-88. 

[31] Yang Fan, Huang Xian-Hui, Li Guang-Hui, Ni Heng-Jia, Zhao Yong-Da, Ding Huan-Zhong, Zeng Zhen-Ling*.

 Estimating tulathromycin withdrawal time in pigs using a physiologically based pharmacokinetics model, Food Additives & Contaminants: Part A, (2013), 30（7）：1255–1263.

[32] Ma, J., J. Liu, L. Lv, Z. Zong, Y. Sun, H. Zheng, Z. Chen, and Z. Zeng*. Characterization of Extended-Spectrum beta-Lactamase Genes Found among Escherichia coli Isolates from Duck and Environmental Samples Obtained on a Duck Farm. Applied and  Environmental Microbiology, (2012), 78(10): 3668-3673.

[33] Hou, J., X. Huang, Y. Deng, L. He, T. Yang, Z. Zeng, Z. Chen, and J. Liu. Dissemination of the Fosfomycin Resistance Gene fosA3 with CTX-M beta-Lactamase Genes and rmtB Carried on IncFII Plasmids among Escherichia coli Isolates from Pets in China. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, (2012), 56(4): 2135-2138. 

[34] Zeng, D., X. Shen, L. He, H. Ding, Y. Tang, Y. Sun, B. Fang, and Z. Zeng*. Liquid chromatography tandem mass spectrometry for the simultaneous determination of mequindox and its metabolites in porcine tissues. JOURNAL OF SEPARATION SCIENCE, (2012), 35(10-11): 1327-1335

[35] Shan, Q., Y. Liu, L. He, H. Ding, X. Huang, F. Yang, Y. Li, and Z. Zeng*, Metabolism of mequindox and its metabolites identification in chickens using LC-LTQ-Orbitrap mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, (2012), 881-882: 96-106. 

[36] Sun, N., J. Liu, F. Yang, D. Lin, G. Li, Z. Chen, Z. Zeng*, Molecular characterization of the antimicrobial resistance of Riemerella anatipestifer isolated from ducks. VETERINARY MICROBIOLOGY, (2012), 158(3-4): 376-383. 

[37] Li, G., F. Yang, L. He, H. Ding, N. Sun, Y. Liu, Y. Liu, Q. Shan, Y. Li, Z. Zeng*, Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration. RESEARCH IN VETERINARY SCIENCE, (2012), 93(3): 1380-1386. 

[38] Xi, W., L. He, C. Guo, Q. Cai, Z. Zeng*, Simultaneous determination of amoxicillin and clavulanic acid in dog plasma by high-performance liquid chromatography tandem mass spectrometry. ANALYTICAL LETTERS, (2012), 45(13): 1764-1776. 

[39] Wang, A., H. Ding, Y. Liu, Y. Gao, Z. Zeng*, Single dose pharmacokinetics of terbinafine in cats. JOURNAL OF FELINE MEDICINE AND SURGERY, (2012), 14(8): 540-544. 

[40] Yang, F., H.W. Liu, M. Li, H.Z. Ding, X.H. Huang, Z.L. Zeng*, Use of a Monte Carlo analysis within a physiologically based pharmacokinetic model to predict doxycycline residue withdrawal time in edible tissues in swine. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, (2012), 29(1): 73-84. 

[41] Jiang, H., D. Lue, Z. Chen, X. Wang, J. Chen, Y. Liu, X. Liao, J. Liu, Z. Zeng*, High prevalence and widespread distribution of multi-resistant Escherichia coli isolates in pigs and poultry in China. VETERINARY JOURNAL, (2011), 187(1): 99-103.

[42] Zheng, Y., Y. Liu, H. Guo, L. He, B. Fang, Z. Zeng*, Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. ANALYTICA CHIMICA ACTA, (2011), 690(2): 269-274.

[43] Guo, H., K. Liu, Y. Liu, B. Fang, M. Liu, L. He, Z. Zeng*, Molecularly imprinted solid-phase extraction for the selective determination of valnemulin in feeds with high performance liquid chromatography. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, (2011),  879(2): 181-185. 

[44 ] Zeng, Z., G. Deng, X. Shen, M. Rizwan-Ul-Haq, D. Zeng, H. Ding, Plasma and tissue pharmacokinetics of danofloxacin in healthy and in experimentally infected chickens with Pasteurella multocida. J Vet Pharmacol Ther, (2011), 34(1): 101-104.

[45] Zeng, D., C. Lin, Z. Zeng*, X. Huang, L. He, Multi-Residue Determination of Eight Anabolic Steroids by GC-MS in Muscle Tissues from Pigs. AGRICULTURAL SCIENCES IN CHINA, (2010), 9(2): 306-312. 

[46] DING, H., Y. LI, Z. CHEN, M. RIZWAN-ul-HAQ, Z. ZENG*, Plasma and tissue cage fluid pharmacokinetics of marbofloxacin after intravenous, intramuscular, and oral single dose application in pigs. Journal of Veterinary Pharmacology and Therapeutics, (2010), 33(5): 507-510.

[47] Zeng, Z*., J. Wu, G. Yang, Z. Chen, X. Huang, and H. Ding, Study of colistin depletion in duck tissues after intramuscular and oral administration. J Vet Pharmacol Ther, (2010), 33(4): 408-410

  选择兽医药理学与毒理学研究方向，它是应用基础学科，与国家的重大需求密切相关。只要脚踏实地，多动脑、多动手实践，努力工作，美好的远景就在你的眼前。