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屈畅

博士,讲师
研究方向:中医药治疗神经系统疾病(阿尔茨海默症、帕金森)的病理机制和药理药效研究
电子邮箱:quchang@scau.edu.cn
     

个人简介


   

2015-2018:广州中医药大学中药学医学硕士;

2018-2021:香港中文大学中药学博士;

20219月至今:就职于

  

承担的主要科研项目:  


  

基于--微生物轴调节JAK/STAT3/GSK3β路探究天麻素抗阿尔茨海默症的作用和机制,2023A04J2261,广州市基础与应用基础研究专题。

代表性论文:



1.GX AiXY WuYX DouRL HuangLJ ZhongYH LiuYF XianZX LinYC LiZR SuJN ChenC Qu.Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating erythrocyte metabolism and Nrf2 signaling pathway. Food Chem Toxicol. 2022,166:113215. (第一通讯作者)

2.Qu C*, Li QP*, Su ZR, Ip SP, Yuan QJ, Xie YL, Xu QQ, Yang W, Huang YF, Xian YF#, Lin ZX#. Nano-Honokiol Ameliorates the Cognitive Deficits in TgCRND8 Mice of Alzheimer’s Disease via Inhibiting Neuropathology and Modulating Gut Microbiota. Journal of advanced research, 2021,35:231-243. (第一作者)

3.Qu C*, Liu L, Xu QQ, Xian YF#, Lin ZX#. Neuroprotective Effects of San-Jia-Fu-Mai Decoction: Studies on the In Vitro and In Vivo Models of Parkinson’s Disease. World Journal of Traditional Chinese Medicine. (第一作者)

4.Qu C*, Yuan ZW*, Yu XT*, Huang YF, Yang GH, Chen JN, Lai XP, Su ZR, Zeng HF#, Xie Y#, Zhang XJ#. Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism. Pharmacological Research. 2017 (121): 70-82. (第一作者)

5.Qu C*, Yang GH*, Zheng RB, Yu XT, Peng SZ, Xie JH, Chen JN, Wang XF, Su ZR#, Zhang XJ#. The immune-regulating effect of Xiao’er Qixingcha in constipated mice induced by high-heat and high-protein diet. BMC Complementary and Alternative Medicine. 2017 (17):185. (第一作者)

6.Zhang XJ*, Yuan ZW*, Qu C*, Yu XT, Huang T, Chen VP, Su ZR, Dou YX, Wu JZ, Zeng HF#, Xie Y#, Chen JN#. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota. Pharmacological Research. 2018 (137): 34-46. (并列第一作者)

7.Xian YF, Qu C, Liu Y, IP SP, Yuan QJ, Yang W, Lin ZX. Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2020(2020): 5920476. (并列第一作者)

 

承担主要课程:


 

《中药药剂学》、《科研创新实验训练》、《中药药剂学实验》

 

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