个人简介

    1975年12月生，1996年于湖南师范大学化学系获理学学士学位，1999年于中山大学化学与化工学院获有机化学专业理学硕士学位，2002年于中科院昆明植物研究所获植物（化）学理学博士学位。德国马普化学生态研究所生物有机化学系博士后。2007年3月至2017年4月受聘为中科院华南植物园研究员，于2008年获中科院‘百人计划’项目支持。2017年5月至今受聘为 教授。主要从事植物功能成分发掘与利用相关的科研与教学工作。近年获得五项国家自然基金面上项目等科研课题十余项，发表论文八十余篇，其中SCI论文五十篇，获授权发明专利21件。任专业期刊《Nat Prod Bioprospect》编委，并为多个SCI期刊评议审稿人。

承担主要科研项目：

1、国家自然科学基金面上项目，青钱柳叶中潜在活性成分的诱导发掘及主要活性成分的结构衍化生成机制（No.32170401），2022.1-2025.12，主持。

2、广东省自然科学基金项目，银合欢豆荚和叶中潜在功能活性成分发掘研究（No.2023A1515012805），2023.1-2025.12，主持。

3、广东省自然科学基金项目，入侵植物阔叶丰花草潜在抗MRSA等功能活性成分发掘研究（No.2019A1515011236），2019.10-2022.9，主持。

4、国家自然科学基金面上项目，三叶木通潜在活性成分诱导发掘及诱导机制研究（No.31470422），2015.1-2018.12，主持。

5、广东省自然科学基金项目，南美蟛蜞菊潜在活性成分的诱导发掘研究（No.2014A030313742），2015.1-2018.1，主持。

6、国家自然科学基金面上项目，三种入侵植物潜在活性成分的诱导发掘及类冠酮素诱导剂的结构优化研究（No.31270406），2013.1-2016.12，主持。

7、国家自然科学基金面上项目，紫茎泽兰调控其活性物质分泌的信号机制研究（No.30970453），2010.1-2012.12，主持

8、国家自然科学基金面上项目，活性JA类似物的合成筛选及对药用植物有效成分的诱导研究（No.30870248），2009.1-2011.12，主持。

代表性论文：

1.Li-Mei Dong, Qiao-Lin Xu, Shao-Bo Liu, Shan-Xuan Zhang, Meng-Fei Liu, Jin-Long Duan, Jin-Kui Ouyang, Jia-Tao Hu, Fen-Yu Fu, Jian-Wen Tan*（通讯作者）. Germacrane sesquiterpene dilactones from Mikania micrantha and their antibacterial and cytotoxic activity. Molecules, 2023, 28(5), 2119. 

2.Tao Lou, Qiao-Lin Xu, Yu-Ling Tan, Shao-Bo Liu, Shan-Xuan Zhang, Ying Zeng, Feng-Qiang Jiang, Jian-Wen Tan*（通讯作者）. Two new germacrane sesquiterpenoids from the inflorescences of Mikania micrantha. Phytochemistry Letters, 2023, 54: 141-145.

3.Shao-Bo Liu, Lei Zeng, Qiao-Lin Xu*, Ying-Le Chen, Tao Lou, Shan-Xuan Zhang, Jian-Wen Tan*（通讯作者）. Polycyclic phenol derivatives from the leaves of Spermacoce latifolia and their antibacterial and α-glucosidase inhibitory activity. Molecules, 2022, 27(10), 3334.

4.Hui Ren, Shao-Bo Liu, Tao Lou, Fen-Yu Fu, Qiao-Lin Xu*, Shan-Xuan Zhang, Jian-Wen Tan*（通讯作者）. Two new ent-kaurane diterpenoids from the leaves of Sphagneticola trilobata. Phytochemistry Letters, 2022, 49: 177-181.

5.Mei Zhang, Jin-Kui Ouyang, Qiao-Lin Xu*, Shao-Bo Liu, Tao Qian, Li-Mei Dong, Jian-Wen Tan*（通讯作者）. Thymol derivatives with antibacterial and cytotoxic activity from the aerial parts of Ageratina adenophora. RSC Advances, 2021, 11(10): 5755-5761.

6.Bi Luo, Li-Mei Dong, Qiao-Lin Xu*, Qiang Zhang, Wen-Bin Liu, Xiao-Yi Wei, Xu Zhang, Jian-Wen Tan*（通讯作者）. Characterization and immunological activity of polysaccharides from Ixeris polycephala. International Journal of Biological Macromolecules, 2018, 113: 804-812.

7.Li-Mei Dong, Li-Lan Huang, Hang Dai, Qiao-Lin Xu, Jin-Kui Ouyang, Xu-Chao Jia, Wen-Xiang Gu*, Jian-Wen Tan*（通讯作者）. Anti-MRSA sesquiterpenes from the semi-mangrove Plant Myoporum Bontioides A. Gray. Marine Drugs, 2018, 16(11): 438.

8.Jin-Kui Ouyang, Li-Mei Dong, Qiao-Lin Xu*, Jing Wang, Shao-Bo Liu, Tao Qian, Yun-Fei Yuan, Jian-Wen Tan*（通讯作者）. Triterpenoids with α-glucosidase inhibitory activity and cytotoxic activity from the leaves of Akebia trifoliata. RSC Advances, 2018, 8: 40483-40489.

9.Qiang Zhang, Qiao-Lin Xu*, Xiao-Mei Xia, Li-Mei Dong, Bi Luo, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. A new phenylpropane-pimarane heterodimer and a new ent-kaurene diterpene from the husks of Oryza sativa. Phytochemistry Letters, 2018, 24: 120-124.

10.Bi Luo, Li-Mei Dong, Qiao-Lin Xu*, Xu Zhang, Qiang Zhang, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. A new monoterpene and a new sesquiterpene from the roots of Ageratina adenophora. Phytochemistry Letters, 2018, 24: 67-70.

11.Li-Mei Dong, Xu-Chao Jia, Qing-Wen Luo, Qiang Zhang, Bi Luo, Wen-Bin Liu, Xu Zhang, Qiao-Lin Xu*, Jian-Wen Tan*（通讯作者）. Phenolics from Mikania micrantha and their antioxidant activity. Molecules, 2017, 22(7), 1140.

12.Ying Luo, Hai-Yan Shen, Qing-Xiang Shen, Chao-Hui Cao, Min Zhang, Shi-Yin Long, Zong-Bao Wang, Jian-Wen Tan*（通讯作者）. A new anthraquinone and a new naphthoquinone from the whole plant of Spermacoce latifolia. Journal of Asian Natural Products Research, 2017, 19(9): 869-876 

13.Li-Mei Dong, Xu-Chao Jia, Qing-Wen Luo, Yi-Ming Peng, Qiang Zhang, Bi Luo, Jian-Wen Tan*（通讯作者）. Four new ent-kaurene diterpene glucosides from Mikania micrantha. Phytochemistry Letters, 2017, 20: 155-159. 

14.Li-Mei Dong, Mei Zhang, Qiao-Lin Xu, Qiang Zhang, Bi Luo, Qing-Wen Luo, Wen-Bin Liu, Jian-Wen Tan*（通讯作者）. Two new thymol derivatives from the Roots of Ageratina adenophora. Molecules, 2017, 22(4), 592.

15.Hui Ren, Qiao-Lin Xu, Mei Zhang, Li-Mei Dong, Qiang Zhang, Bi Luo, Qin-Wen Luo, Jian-Wen Tan*（通讯作者）. Bioactive caffeic acid derivatives from Wedelia trilobata. Phytochemistry Letters, 2017, 19: 18-22.

16.Qiao-Lin Xu, Jing Wang, Li-Mei Dong, Qiang Zhang, Bi Luo, Yong-Xia Jia, Hong-Feng Wang, Jian-Wen Tan*（通讯作者）. Two new pentacyclic triterpene saponins from the leaves of Akebia trifoliata. Molecules, 2016, 21(7), 962.

17.Jing Wang, Hui Ren, Qiao-Lin Xu, Zhong-Yu Zhou, Ping Wu, Xiao-Yi Wei, Yong Cao, Xue-Xiang Chen, Jian-Wen Tan*（通讯作者）. Antibacterial oleanane-type triterpenoids from pericarps of Akebia trifoliata. Food Chemistry. 2015, 168: 623-629.

18.Hui Ren, Qiao-Lin Xu, Ying Luo, Mei Zhang, Zhong-Yu Zhou, Li-Mei Dong, Jian-Wen Tan*（通讯作者）. Two new ent-kaurane diterpenoids from Wedelia trilobata (L.) Hitchc. Phytochemistry Letters, 2015, 11: 260-263.

19.Meng-Fei Zheng, Hui Ren, Ying Luo, Li-Mei Dong, Ling-Qiong Wang, Zhong-Yu Zhou, Jian-Wen Tan*（通讯作者）. A new diantheramide and a new cyclic peptide from the seeds of Vaccaria hispanica. Phytochemistry Letters, 2015, 11: 240-244.

20.Ying Luo, Qiao-Lin Xu, Li-Mei Dong, Zhong-Yu Zhou, Yu-Chan Chen, Wei-Min Zhang, Jian-Wen Tan*（通讯作者）. A new ursane and a new oleanane triterpene acids from the whole plant of Spermacoce latifolia. Phytochemistry Letters, 2015, 11: 127-131.

21.Jing Wang, Qiao-Lin Xu, Meng-Fei Zheng, Hui Ren, Ting Lei, Ping Wu, Zhong-Yu Zhou, Xiao-Yi Wei, and Jian-Wen Tan*（通讯作者）. Bioactive 30-noroleanane triterpenes from the pericarps of Akebia trifoliata. Molecules, 2014, 19(4): 4301-4312.

22.Qiao-Lin Xu, Mei Zhang, Zhong-Yu Zhou^#, Wan-Xue Liu, Fang-Hao Wan, Hong-Feng Wang, Jian-Wen Tan*（通讯作者）. Two new carene-type monoterpenes from aerial parts of Ageratina adenophora. Phytochemistry Letters, 2014, 9: 123-126.

23.Zhong-Yu Zhou, Wan-Xue Liu, Gang Pei, Hui Ren, Jing Wang, Qiao-Lin Xu, Hai-Hui Xie, Fang-Hao Wan, Jian-Wen Tan*（通讯作者）. Phenolic compounds from Ageratina adenophora roots and their allelopathic effects on Arabidopsis seeds germination and seedling growth. Journal of Agricultural and Food Chemistry, 2013, 61(48): 111792-111799.

24.Mei Zhang, Wan-Xue Liu, Meng-Fei Zheng, Qiao-Lin Xu, Fang-Hao Wan, Jing Wang, Ting Lei, Zhong-Yu Zhou, Jian-Wen Tan*（通讯作者）. Bioactive quinic acid derivatives from Ageratina adenophora. Molecules, 2013, 18(11): 14096-14104. 

25.Jian Yan^#, Li-Rong Sun^#, Zhong-Yu Zhou^#, Yu-Chan Chen, Wei-Min Zhang, Hao-Fu Dai, and Jian-Wen Tan*（通讯作者）. Homoisoflavonoids from the medicinal plant Portulaca oleracea. Phytochemistry, 2012, 80: 37-41. 

26.Jian Yan, Zhong-Yu Zhou, Mei Zhang, Jing Wang, Hao-Fu Dai, and Jian-Wen Tan*（通讯作者）. New serratene triterpenoids from Palhinhaea cernua and their cytotoxic activity. Planta Medica, 2012, 78(12): 1387-1391.

27.Mei Zhang, Zhong-Yu Zhou, Jing Wang, Yong Cao, Xue-Xiang Chen, Wei-Min Zhang, Li-Dong Lin, and Jian-Wen Tan*（通讯作者）. Phytoecdysteroids from the roots of Achyranthes bidentata Blume. Molecules, 2012, 17(3): 3324-3332.

承担主要课程：

《中药化学》、《森林植物资源开发与利用》