Huang Youhua
Personal profile:
Huang Youhua: Male, Hubei Badong, Ph.D., researcher. Research direction: anti-disease immune mechanism and development of anti-disease products for marine fish. In recent years, he has presided over 3 national-level projects, including the National Natural Science Foundation of China and the 973 sub-project; published the 15th SCI papers by the first author or correspondent author (including the co-first and co-author); 3 pieces; participated in the preparation of 2 monographs.
work experience:
2010.12-present Associate Research Fellow, South China Sea Institute of
Oceanology, Chinese Academy of Sciences 2010.4-2010.12 Assistant Researcher, South China Sea Institute of Oceanology, Chinese Academy of Sciences
2007.9-2010.3 Sun Yat-Sen University Postdoctoral
Education experience:
2002.9-2007.7 Institute of Hydrobiology, Chinese Academy of Sciences,
Department of Aquatic Biology, 1998.9-2002.7 Bachelor of Science in Biotechnology
Honorary title:
Guangdong Province Special Support Program “Hundreds of Million Project Young Talents”
Research projects:
1. National Natural Science Foundation of China, the mechanism of action of lysosomal pathway in SGIV induced apoptosis of grouper iridescent virus, 2015.1-2018.12, 800,000, under research, host.
2. National Natural Science Foundation of China, the role of the grouper triple-order protein TRIM in antiviral natural immune response, 2012.1-2015.12, 620,000, completed, presided over.
3.973 sub-topic, 2012CB114404, the immune response and regulation network of fish response to iridescent virus infection, 2012.1-2016.12, 536,800, conclusion, presiding.
Published papers:
1.Huang YH, Yang M, Yu YP, Yang Y, Zhou LL, Huang XH, Qin QW. Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. Fish Shellfish Immunol. 2016, 5:106-15.
2. Huang YH, Yu YP, Yang Y, Yang M, Zhou LL, Huang XH, Qin QW. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish Shellfish Immunol. 2016, 54:435-44.
3. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, Qin Q. Antiviral function of grouper MDA5 against iridovirus and nodavirus. Fish Shellfish Immunol. 2016, 54:188-96.
4. Yu Y, Huang X, Zhang J, Liu J, Hu Y, Yang Y, Cai J, Huang Y**, Qin Q*. Fish TRIM16L exerts negative regulation on antiviral immune response against grouper iridoviruses. Fish Shellfish Immunol. 2016,59:256-267.
5. Yu Y, Huang X, Liu J, Zhang J, Hu Y, Yang Y, Huang Y**, Qin Q*. Fish TRIM32 functions as a critical antiviral molecule against iridovirus and nodavirus. Fish Shellfish Immunol. 2016, 60:33-43.
6. Gao EB, Huang Y**, Ning D*. Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution. Genes (Basel). 2016, 7(10).
7. Huang Y, Ouyang Z, Wang W, Yu Y, Li P, Zhou S, Wei S, Wei J, Huang X, Qin Q.
Antiviral role of grouper STING against iridovirus infection. Fish Shellfish Immunol. 2015, 47(1):157-67.
8. Huang Y, Huang X, Yang Y, Wang W, Yu Y, Qin Q. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in nodavirus infection induced cell death. Fish Shellfish Immunol. 2015, 43(1):241-8.
9. Huang Y, Huang X, Cai J, OuYang Z, Wei S, Wei J, Qin Q. Identification of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 3 involved in antiviral immune response against fish RNA virus. Fish Shellfish Immunol. 2015, 42(2):345-52.
10. Huang YH, Huang XH, Zhengling OY, Wei SN, Guo CY, Qin QW. Development of a new cell line from the snout of giant grouper, Epinephelus lanceolatus (Bloch), and its application in iridovirus and nodavirus pathogenesis. Aquaculture. 2014, 432: 265-272.
11. Xu L, Feng J, Huang Y*. identification of lymphocystis disease virus from paradise fish Macropodus opercularis (LCDV-PF). Arch Virol. 2014,159(9):2445-9.
12. Huang Y, Huang X, Yan Y, Cai J, Ouyang Z, Cui H, Wang P, Qin Q. Transcriptome analysis of orange-spotted grouper (Epinephelus coioides) spleen in response to Singapore grouper iridovirus. BMC Genomics. 2011,12:556.
13. Huang Y, Huang X, Cai J, Ye F, Qin Q. Involvement of the mitogen-activated protein kinase pathway in soft-shelled turtle iridovirus-induced apoptosis. Apoptosis. 2011, 16(6):581-93.
14. Huang Y, Huang X, Cai J, Ye F, Guan L, Liu H, Qin Q. Construction of green fluorescent protein-tagged recombinant iridovirus to assess viral replication. Virus Res. 2011, 160(1-2):221-9.
15. Gong J#, Huang Y##, Huang X, Ouyang Z, Guo M, Qin Q. Establishment and characterization of a new cell line derived from kidney of grouper, Epinephelus akaara (Temminck & Schlegel), susceptible to Singapore grouper iridovirus (SGIV). J Fish Dis. 2011, 34(9):677-86.
Publication of books and textbooks:
Participated in the compilation of Chen Songlin, Qin Qiwei, The Theory and Technology of Fish Cell Culture, Science Press, 2011; Wang Jianguo, Fish Diseases, China Agricultural Press, 2013.